CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione S-transferase DHAR3 chloroplastic

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q9FWR4
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
1.8.5.1
Glutathione dehydrogenase (ascorbate).
based on mapping to UniProt Q9FWR4
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.

UniProtKB Entries (1)

Q9FWR4
DHAR1_ARATH
Arabidopsis thaliana
Glutathione S-transferase DHAR1, mitochondrial

PDB Structure

PDB 5ELA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Arabidopsis thaliana DHAR1 apo structure
Menault, M., Roszak, A.W., Lapthorn, A.J.
To Be Published