CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family

Enzyme Information

4.1.2.10
(R)-mandelonitrile lyase.
based on mapping to UniProt O24243
(R)-mandelonitrile = cyanide + benzaldehyde.
-!- A variety of enzymes from different sources and with different properties. -!- Some are flavoproteins, others are not. -!- Active toward a number of aromatic and aliphatic hydroxynitriles (cyanohydrins).

UniProtKB Entries (1)

O24243
MDL1_PRUDU
Prunus dulcis
(R)-mandelonitrile lyase 1

PDB Structure

PDB 5EB5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of almond hydroxynitrile lyase isoenzyme 5 provide a rationale for the lack of oxidoreductase activity in flavin dependent HNLs.
Pavkov-Keller, T., Bakhuis, J., Steinkellner, G., Jolink, F., Keijmel, E., Birner-Gruenberger, R., Gruber, K.
J.Biotechnol.