1 keywords

CATH Domain 5e6pB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.42 Pdz3 Domain
Homologous Superfamily 2.30.42.10 PDZ domain

Domain Context

CATH Clusters

Superfamily 2.30.42.10
Functional Family Rho guanine nucleotide exchange factor (GEF) 11

Enzyme Information

UniProtKB Entries (2)

B2RXS4
PLXB2_MOUSE
Mus musculus
Plexin-B2
O15085
ARHGB_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 11

PDB Structure

PDB 5E6P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Pascoe, H.G., Gutowski, S., Chen, H., Brautigam, C.A., Chen, Z., Sternweis, P.C., Zhang, X.
Proc.Natl.Acad.Sci.USA