CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Carbonic anhydrase 2

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt Q8N1Q1
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

Q8N1Q1
CAH13_HUMAN
Homo sapiens
Carbonic anhydrase 13

PDB Structure

PDB 5E2N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases.
Zubriene, A., Smirnov, A., Dudutiene, V., Timm, D.D., Matuliene, J., Michailoviene, V., Zaksauskas, A., Manakova, E., Grazulis, S., Matulis, D.
ChemMedChem