CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione S-transferase DHAR3 chloroplastic

Enzyme Information

1.8.5.1
Glutathione dehydrogenase (ascorbate).
based on mapping to UniProt Q65XA0
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate.
2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q65XA0
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

Q65XA0
DHAR1_ORYSJ
Oryza sativa Japonica Group
Probable glutathione S-transferase DHAR1, cytosolic

PDB Structure

PDB 5D9T
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica
Do, H., Kim, I.S., Jeon, B.W., Lee, C.W., Park, A.K., Wi, A.R., Shin, S.C., Park, H., Kim, Y.S., Yoon, H.S., Kim, H.W., Lee, J.H.
Sci Rep