CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.120 | Anthranilate synthase |
|
3.60.120.10 | Anthranilate synthase |
Domain Context
CATH Clusters
| Superfamily | Anthranilate synthase |
| Functional Family | Anthranilate synthase component 1 |
Enzyme Information
| 4.1.3.27 |
Anthranilate synthase.
based on mapping to UniProt P9WFX2
Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.2.1.20 and EC 5.3.1.24). -!- The native enzyme in the complex with uses either glutamine or (less efficiently) NH(3). -!- The enzyme separated from the complex uses NH(3) only.
|
UniProtKB Entries (1)
| P9WFX2 |
TRPE_MYCTO
Mycobacterium tuberculosis CDC1551
Anthranilate synthase component 1
|
PDB Structure
| PDB | 5CWA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.
Acta Crystallogr.,Sect.D
|
