CATH Classification

Domain Context

CATH Clusters

Superfamily Anticodon-binding domain
Functional Family Putative dna polymerase subunit gamma-2 mitochondrial

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UHN1
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P54098
DPOG1_HUMAN
Homo sapiens
DNA polymerase subunit gamma-1

PDB Structure

PDB 5C51
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Sohl, C.D., Szymanski, M.R., Mislak, A.C., Shumate, C.K., Amiralaei, S., Schinazi, R.F., Anderson, K.S., Yin, Y.W.
Proc.Natl.Acad.Sci.USA