CATH Classification

Domain Context

CATH Clusters

Superfamily Glucose-6-phosphate isomerase like protein; domain 1
Functional Family

Enzyme Information

5.3.1.28
D-sedoheptulose 7-phosphate isomerase.
based on mapping to UniProt Q47VU0
D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate.
-!- In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core. -!- In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.

UniProtKB Entries (1)

Q47VU0
GMHA_COLP3
Colwellia psychrerythraea 34H
Phosphoheptose isomerase

PDB Structure

PDB 5BY2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure and Comparative Sequence Analysis of GmhA from Colwellia psychrerythraea Strain 34H Provides Insight into Functional Similarity with DiaA
Do, H., Yun, J.S., Lee, C.W., Choi, Y.J., Kim, H.Y., Kim, Y.J., Park, H., Chang, J.H., Lee, J.H.
Mol.Cells