CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1600 | SIR2/SIRT2 'Small Domain' |
|
3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
| Superfamily | SIR2/SIRT2 'Small Domain' |
| Functional Family |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt Q96EB6
|
UniProtKB Entries (1)
| Q96EB6 |
SIR1_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-1
|
PDB Structure
| PDB | 5BTR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Genes Dev.
|