CATH Domain 5b8iA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.21	Purple Acid Phosphatase; chain A, domain 2
	3.60.21.10	Metallo-dependent phosphatases

Domain Context

CATH Clusters

Superfamily	3.60.21.10
Functional Family	Serine/threonine-protein phosphatase

Enzyme Information

UniProtKB Entries (1)

J3K8M7_COCIM

Coccidioides immitis RS

Serine/threonine-protein phosphatase

PDB Structure

PDB	5B8I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Juvvadi, P.R., Fox 3rd, D., Bobay, B.G., Hoy, M.J., Gobeil, S.M.C., Venters, R.A., Chang, Z., Lin, J.J., Averette, A.F., Cole, D.C., Barrington, B.C., Wheaton, J.D., Ciofani, M., Trzoss, M., Li, X., Lee, S.C., Chen, Y.L., Mutz, M., Spicer, L.D., Schumacher, M.A., Heitman, J., Steinbach, W.J. Nat Commun