CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Probable 2-ketogluconate reductase

Enzyme Information

1.1.1.26
Glyoxylate reductase.
based on mapping to UniProt Q8U3Y2
Glycolate + NAD(+) = glyoxylate + NADH.
-!- Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.

UniProtKB Entries (1)

Q8U3Y2
GYAR_PYRFU
Pyrococcus furiosus DSM 3638
Glyoxylate reductase

PDB Structure

PDB 5AOV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
New Insights Into the Mechanism of Substrates Trafficking in Glyoxylate/Hydroxypyruvate Reductases.
Lassalle, L., Engilberge, S., Madern, D., Vauclare, P., Franzetti, B., Girard, E.
Sci.Rep.