CATH Classification

Domain Context

CATH Clusters

Superfamily Hypothetical protein af1432
Functional Family Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Enzyme Information

3.1.5.-
Triphosphoric monoester hydrolases.
based on mapping to UniProt Q9Y3Z3

UniProtKB Entries (1)

Q9Y3Z3
SAMH1_HUMAN
Homo sapiens
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

PDB Structure

PDB 5AO3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Arnold, L.H., Groom, H.C.T., Kunzelmann, S., Schwefel, D., Caswell, S.J., Ordonez, P., Mann, M.C., Rueschenbaum, S., Goldstone, D.C., Pennell, S., Howell, S.A., Stoye, J.P., Webb, M., Taylor, I.A., Bishop, K.N.
Plos Pathog.