CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family DDB1 and CUL4-associated factor 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9Y4B6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (3)

Q7ZB17
Q7ZB17_SIV
Simian immunodeficiency virus
Protein Vpr
H6WEA4
H6WEA4_MANSP
Mandrillus sphinx
SAM domain and HD domain-containing protein 1
Q9Y4B6
DCAF1_HUMAN
Homo sapiens
DDB1- and CUL4-associated factor 1

PDB Structure

PDB 5AJA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx.
Schwefel, D., Boucherit, V.C., Christodoulou, E., Walker, P.A., Stoye, J.P., Bishop, K.N., Taylor, I.A.
Cell Host Microbe.