CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family 3-phosphoinositide-dependent protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15530
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15530
PDPK1_HUMAN
Homo sapiens
3-phosphoinositide-dependent protein kinase 1

PDB Structure

PDB 5ACK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods.
Kroon, E., Schulze, J.O., Suss, E., Camacho, C.J., Biondi, R.M., Domling, A.
Angew.Chem.Int.Ed.Engl.