CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Cyclin-K (Predicted)

Enzyme Information

UniProtKB Entries (1)

Q9NYV4
CDK12_HUMAN
Homo sapiens
Cyclin-dependent kinase 12

PDB Structure

PDB 5ACB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Covalent Targeting of Remote Cysteine Residues to Develop Cdk12 and Cdk13 Inhibitors.
Zhang, T., Kwiatkowski, N., Olson, C.M., Dixon-Clarke, S.E., Abraham, B.J., Greifenberg, A.K., Ficarro, S.B., Elkins, J.M., Liang, Y., Hannett, N.M., Manz, T., Hao, M., Bartkowiak, B., Greenleaf, A.L., Marto, J.A., Geyer, M., Bullock, A.N., Young, R.A., Gray, N.S.
Nat.Chem.Biol.