CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione S-transferase F2

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P46422
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P46422
GSTF2_ARATH
Arabidopsis thaliana
Glutathione S-transferase F2

PDB Structure

PDB 5A5K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands.
Ahmad, L., Rylott, E.L., Bruce, N.C., Edwards, R., Grogan, G.
FEBS Open Bio