CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Carbonic anhydrase 2

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P00921
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00921
CAH2_BOVIN
Bos taurus
Carbonic anhydrase 2

PDB Structure

PDB 5A25
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Rational Engineering of a Mesohalophilic Carbonic Anhydrase to an Extreme Halotolerant Biocatalyst.
Warden, A.C., Williams, M., Peat, T.S., Seabrook, S.A., Newman, J., Dojchinov, G., Haritos, V.S.
Nat.Commun.