CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.300.10
Functional Family S-adenosylmethionine synthase

Enzyme Information

2.5.1.6
Methionine adenosyltransferase.
based on mapping to UniProt P31153
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L- methionine.
-!- Formerly EC 2.4.2.13.

UniProtKB Entries (1)

P31153
METK2_HUMAN
Homo sapiens
S-adenosylmethionine synthase isoform type-2

PDB Structure

PDB 5A1I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
Murray, B., Antonyuk, S.V., Marina, A., Lu, S.C., Mato, J.M., Hasnain, S.S., Rojas, A.L.
Proc.Natl.Acad.Sci.USA