CATH Domain 4zy3A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.120	6 Propeller
	2.120.10	Neuraminidase
	2.120.10.80	Kelch-type beta propeller

Domain Context

CATH Clusters

Superfamily	Kelch-type beta propeller
Functional Family	Kelch-like ECH-associated protein 1

Enzyme Information

UniProtKB Entries (1)

KEAP1_MOUSE

Mus musculus

Kelch-like ECH-associated protein 1

PDB Structure

PDB	4ZY3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Saito, T., Ichimura, Y., Taguchi, K., Suzuki, T., Mizushima, T., Takagi, K., Hirose, Y., Nagahashi, M., Iso, T., Fukutomi, T., Ohishi, M., Endo, K., Uemura, T., Nishito, Y., Okuda, S., Obata, M., Kouno, T., Imamura, R., Tada, Y., Obata, R., Yasuda, D., Takahashi, K., Fujimura, T., Pi, J., Lee, M.S., Ueno, T., Ohe, T., Mashino, T., Wakai, T., Kojima, H., Okabe, T., Nagano, T., Motohashi, H., Waguri, S., Soga, T., Yamamoto, M., Tanaka, K., Komatsu, M. Nat Commun