CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.40.1840
Functional Family Aminopeptidase N

Enzyme Information

3.4.11.-
Aminopeptidases.
based on mapping to UniProt O96935

UniProtKB Entries (1)

O96935
AMP1_PLAFQ
Plasmodium falciparum FcB1/Columbia
M1 family aminopeptidase

PDB Structure

PDB 4ZW7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.