CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.800 | Anticodon-binding domain |
Domain Context
CATH Clusters
| Superfamily | Anticodon-binding domain |
| Functional Family | Putative dna polymerase subunit gamma-2 mitochondrial |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UHN1
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
| Q9UHN1 |
DPOG2_HUMAN
Homo sapiens
DNA polymerase subunit gamma-2, mitochondrial
|
PDB Structure
| PDB | 4ZTU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for processivity and antiviral drug toxicity
in human mitochondrial DNA replicase
EMBO J.
|