CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1740 | Rna Polymerase Sigma Factor; Chain: A |
|
1.10.1740.10 | RNA polymerase sigma factor, region 2, helix turn helix motif |
Domain Context
CATH Clusters
| Superfamily | 1.10.1740.10 |
| Functional Family |
Enzyme Information
| 1.1.1.267 |
1-deoxy-D-xylulose-5-phosphate reductoisomerase.
based on mapping to UniProt B7H1U5
2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH.
-!- The enzyme from several eubacteria, including Escherichia coli, forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis. -!- The mechanism has been shown to be a retroaldol/aldol reaction.
|
UniProtKB Entries (1)
| B7H1U5 |
DXR_ACIB3
Acinetobacter baumannii AB307-0294
1-deoxy-D-xylulose 5-phosphate reductoisomerase
|
PDB Structure
| PDB | 4ZN6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
X-ray Crystal Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Acinetobacter baumannii
to be published
|