CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.70 | Distorted Sandwich |
|
2.70.170 | Acetylcholine Binding Protein; Chain: A, |
|
2.70.170.10 | Neurotransmitter-gated ion-channel ligand-binding domain |
Domain Context
CATH Clusters
| Superfamily | Neurotransmitter-gated ion-channel ligand-binding domain |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| Q8WSF8 |
Q8WSF8_APLCA
Aplysia californica
Soluble acetylcholine receptor
|
| P02708 |
ACHA_HUMAN
Homo sapiens
Acetylcholine receptor subunit alpha
|
PDB Structure
| PDB | 4ZJS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.
J. Neurosci.
|