CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P62593
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P62593
BLAT_ECOLX
Escherichia coli
Beta-lactamase TEM

PDB Structure

PDB 4ZJ3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Exploring the potential impact of an expanded genetic code on protein function.
Xiao, H., Nasertorabi, F., Choi, S.H., Han, G.W., Reed, S.A., Stevens, R.C., Schultz, P.G.
Proc.Natl.Acad.Sci.USA