CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Thioredoxin-like reductase Rv2466c

Enzyme Information

UniProtKB Entries (1)

O53193
TRLR_MYCTU
Mycobacterium tuberculosis H37Rv
Thioredoxin-like reductase Rv2466c

PDB Structure

PDB 4ZIL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.
Albesa-Jove, D., Comino, N., Tersa, M., Mohorko, E., Urresti, S., Dainese, E., Chiarelli, L.R., Pasca, M.R., Manganelli, R., Makarov, V., Riccardi, G., Svergun, D.I., Glockshuber, R., Guerin, M.E.
J.Biol.Chem.