CATH Classification

Domain Context

CATH Clusters

Superfamily Flavin prenyltransferase-like
Functional Family Flavin prenyltransferase UbiX

Enzyme Information

2.5.1.129
Flavin prenyltransferase.
based on mapping to UniProt Q9HX08
Dimethylallyl phosphate + FMNH(2) = prenylated FMNH(2) + phosphate.
-!- The enzyme produces the modified flavin cofactor prenylated FMNH(2), which is required by EC 4.1.1.98 and EC 4.1.1.102. -!- The enzyme acts as a flavin prenyltransferase, linking a dimethylallyl moiety to the flavin N-5 and C-6 atoms and thus adding a fourth non-aromatic ring to the flavin isoalloxazine group.

UniProtKB Entries (1)

Q9HX08
UBIX_PSEAE
Pseudomonas aeruginosa PAO1
Flavin prenyltransferase UbiX

PDB Structure

PDB 4ZAY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis.
White, M.D., Payne, K.A., Fisher, K., Marshall, S.A., Parker, D., Rattray, N.J., Trivedi, D.K., Goodacre, R., Rigby, S.E., Scrutton, N.S., Hay, S., Leys, D.
Nature