CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P15273
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P15273
YOPH_YEREN
Yersinia enterocolitica
Tyrosine-protein phosphatase YopH

PDB Structure

PDB 4Z6B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.
Moise, G., Gallup, N.M., Alexandrova, A.N., Hengge, A.C., Johnson, S.J.
Biochemistry