CATH Domain 4z21A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1000	Arf Nucleotide-binding Site Opener; domain 2
	1.10.1000.11	Arf Nucleotide-binding Site Opener,domain 2

Domain Context

CATH Clusters

Superfamily	Arf Nucleotide-binding Site Opener,domain 2
Functional Family	Cytohesin 1

Enzyme Information

UniProtKB Entries (1)

CYH2_HUMAN

Homo sapiens

Cytohesin-2

PDB Structure

PDB	4Z21
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Lack of evidence that CYTH2/ARNO functions as an intracellular EGFR activator Anastasi, S., Zhu, S.J., Ballaro, C., Manca, S., Lamberti, D., Wang, L.J., Alema, S., Yun, C.H., Segatto, O. To Be Published