CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Transcription initiation factor TFIID subunit

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P21675
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P21675
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

P62805
H4_HUMAN
Homo sapiens
Histone H4

PDB Structure

PDB 4YYM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Flynn, E.M., Huang, O.W., Poy, F., Oppikofer, M., Bellon, S.F., Tang, Y., Cochran, A.G.
Structure