CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C
Functional Family Anthranilate phosphoribosyltransferase

Enzyme Information

2.4.2.18
Anthranilate phosphoribosyltransferase.
based on mapping to UniProt P00500
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

P00500
TRPD_ACIAD
Acinetobacter baylyi ADP1
Anthranilate phosphoribosyltransferase

PDB Structure

PDB 4YI7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate inhibition of protein in tryptophan biosynthesis pathway redirects flux to aromatic catabolism in Acinetobacter baylyi ADP1.
Evans, G.E., Nigon, L.V., Ponniah, K., Burr, N., Anderson, B.F., Norris, G.E., Patrick, W.M.
To Be Published