CATH Classification

Domain Context

CATH Clusters

Superfamily C-terminal domain of ProRS
Functional Family Bifunctional glutamate/proline--tRNA ligase

Enzyme Information

6.1.1.15
Proline--tRNA ligase.
based on mapping to UniProt Q8I5R7
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).

UniProtKB Entries (1)

Q8I5R7
SYP_PLAF7
Plasmodium falciparum 3D7
Proline--tRNA ligase

PDB Structure

PDB 4YDQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis
Jain, V., Yogavel, M., Oshima, Y., Kikuchi, H., Touquet, B., Hakimi, M.A., Sharma, A.
Structure