CATH Classification

Domain Context

CATH Clusters

Superfamily Beta Polymerase, domain 2
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9NP87
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9NP87
DPOLM_HUMAN
Homo sapiens
DNA-directed DNA/RNA polymerase mu

PDB Structure

PDB 4YD1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Creative template-dependent synthesis by human polymerase mu.
Moon, A.F., Gosavi, R.A., Kunkel, T.A., Pedersen, L.C., Bebenek, K.
Proc.Natl.Acad.Sci.USA