CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt Q2T7H6
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

Q2T7H6
LEU3_BURTA
Burkholderia thailandensis E264
3-isopropylmalate dehydrogenase

PDB Structure

PDB 4XXV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD
Seattle Structural Genomics Center for Infectious Disease (SSGCID), Abendroth, J., Dranow, D.M., Lorimer, D.D., Edwards, T.E.
to be published