CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.920
Functional Family ATP-dependent RNA helicase DDX1

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q92499
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q92499
DDX1_HUMAN
Homo sapiens
ATP-dependent RNA helicase DDX1

PDB Structure

PDB 4XW3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.
Kellner, J.N., Meinhart, A.
Acta Crystallogr.,Sect.F