CATH Classification

Domain Context

CATH Clusters

Superfamily Cysteine proteinases
Functional Family PAN2-PAN3 deadenylation complex catalytic subunit PAN2

Enzyme Information

3.1.13.4
Poly(A)-specific ribonuclease.
based on mapping to UniProt P53010
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.

UniProtKB Entries (1)

P53010
PAN2_YEAST
Saccharomyces cerevisiae S288C
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

PDB Structure

PDB 4XR7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase.
Schafer, I.B., Rode, M., Bonneau, F., Schussler, S., Conti, E.
Nat. Struct. Mol. Biol.