CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1410 | Poly(a)-polymerase, middle domain |
|
1.10.1410.20 | 2'-5'-oligoadenylate synthetase 1, domain 2 |
Domain Context
CATH Clusters
| Superfamily | 2'-5'-oligoadenylate synthetase 1, domain 2 |
| Functional Family | 2'-5'-oligoadenylate synthetase 1 |
Enzyme Information
UniProtKB Entries (1)
| Q15646 |
OASL_HUMAN
Homo sapiens
2'-5'-oligoadenylate synthase-like protein
|
PDB Structure
| PDB | 4XQ7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.
Nucleic Acids Res.
|
