CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family NH(3)-dependent NAD(+) synthetase

Enzyme Information

6.3.1.5
NAD(+) synthase.
based on mapping to UniProt Q9HUP3
ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
-!- L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).

UniProtKB Entries (1)

Q9HUP3
NADE_PSEAE
Pseudomonas aeruginosa PAO1
NH(3)-dependent NAD(+) synthetase

PDB Structure

PDB 4XFD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of a NH(3)-dependent NAD(+) synthetase from Pseudomonas aeruginosa
Dranow, D.M., Lorimer, D., Edwards, T.E.
to be published