CATH Classification
Level | CATH Code | Description |
---|---|---|
6 | Special | |
6.10 | Helix non-globular | |
6.10.240 | ProC C-terminal domain-like fold | |
6.10.240.10 |
Domain Context
CATH Clusters
Superfamily | 6.10.240.10 |
Functional Family |
Enzyme Information
1.1.1.382 |
Ketol-acid reductoisomerase (NAD(+)).
based on mapping to UniProt Q64BR7
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD(+) = (2S)-2-hydroxy-2-methyl- 3-oxobutanoate + NADH.
-!- The enzyme, characterized from the bacteria Thermacetogenium phaeum and Desulfococcus oleovorans and from the archaeon Archaeoglobus fulgidus, is specific for NADH (cf. EC 1.1.1.86 and EC 1.1.1.383).
|
UniProtKB Entries (1)
Q64BR7 |
ILVC_UNCAG
uncultured archaeon GZfos26G2
Ketol-acid reductoisomerase (NAD(+))
|
PDB Structure
PDB | 4XDY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Biochem.J.
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