CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.130 | 7 Propeller |
|
2.130.10 | Methylamine Dehydrogenase; Chain H |
|
2.130.10.10 | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | YVTN repeat-like/Quinoprotein amine dehydrogenase |
| Functional Family | Methylosome protein 50 |
Enzyme Information
UniProtKB Entries (1)
| O14744 |
ANM5_HUMAN
Homo sapiens
Protein arginine N-methyltransferase 5
|
PDB Structure
| PDB | 4X63 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Nat.Chem.Biol.
|