1 keywords

CATH Domain 4x46A01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.970 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3
Homologous Superfamily 1.20.970.10 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C

Domain Context

CATH Clusters

Superfamily Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C
Functional Family Thymidine phosphorylase

Enzyme Information

2.4.2.4
Thymidine phosphorylase.
based on mapping to UniProt Q7CP66
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

Q7CP66
TYPH_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Thymidine phosphorylase

PDB Structure

PDB 4X46
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A
Balaev, V.V., Lashkov, A.A., Prokofev, I.I., Gabdoulkhakov, A.G., Betzel, C., Mikhailov, A.M.
To Be Published