1 keywords

CATH Domain 4x2qA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.309 Aldehyde Dehydrogenase; Chain A, domain 2
Homologous Superfamily 3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family Mitochondrial aldehyde dehydrogenase 2

Enzyme Information

1.2.1.36
Retinal dehydrogenase.
based on mapping to UniProt O94788
Retinal + NAD(+) + H(2)O = retinoate + NADH.
-!- Acts on both the 11-trans- and 13-cis-forms of retinal.

UniProtKB Entries (1)

O94788
AL1A2_HUMAN
Homo sapiens
Retinal dehydrogenase 2

PDB Structure

PDB 4X2Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis and In Vitro Testing of Bisdichloroacetyldiamine Analogs for Use as a Reversible Male Contraceptive
Goldstein, A.S., Paik, J., Moreb, J., Haenisch, M., Le Trong, I., Stenkamp, R.E., Petrie, A.G., Smith, N., Mallochowski, W.P., Amory, J.K.
To Be Published