CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphotransferase system, lactose/cellobiose-type IIA subunit
Functional Family serine/threonine-protein kinase ULK3 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q6PHR2
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P53990
IST1_HUMAN
Homo sapiens
IST1 homolog

PDB Structure

PDB 4WZX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
Caballe, A., Wenzel, D.M., Agromayor, M., Alam, S.L., Skalicky, J.J., Kloc, M., Carlton, J.G., Labrador, L., Sundquist, W.I., Martin-Serrano, J.
Elife