CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.160 | Double Stranded RNA Binding Domain |
|
3.30.160.20 |
Domain Context
CATH Clusters
| Superfamily | 3.30.160.20 |
| Functional Family | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform X1 |
Enzyme Information
| 1.3.1.91 |
tRNA-dihydrouridine(20) synthase (NAD(P)(+)).
based on mapping to UniProt Q9NX74
5,6-dihydrouracil(20) in tRNA + NAD(P)(+) = uracil(20) in tRNA + NAD(P)H.
-!- The enzyme specifically modifies uracil(20) in tRNA.
|
UniProtKB Entries (1)
| Q9NX74 |
DUS2L_HUMAN
Homo sapiens
TRNA-dihydrouridine(20) synthase [NAD(P)+]-like
|
PDB Structure
| PDB | 4WFT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Nucleic Acids Res.
|