CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 1
Functional Family Aldehyde dehydrogenase, mitochondrial

Enzyme Information

1.2.1.36
Retinal dehydrogenase.
based on mapping to UniProt P00352
Retinal + NAD(+) + H(2)O = retinoate + NADH.
-!- Acts on both the 11-trans- and 13-cis-forms of retinal.
1.2.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt P00352

UniProtKB Entries (1)

P00352
AL1A1_HUMAN
Homo sapiens
Retinal dehydrogenase 1

PDB Structure

PDB 4WB9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Morgan, C.A., Hurley, T.D.
Chem.Biol.Interact.