CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Fibroblast growth factor receptor

Enzyme Information

UniProtKB Entries (1)

D3DSX2
D3DSX2_HUMAN
Homo sapiens
Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b

PDB Structure

PDB 4V05
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4
Tucker, J.A., Klein, T., Breed, J., Breeze, A.L., Overman, R., Phillips, C., Norman, R.A.
Structure