CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

P25440
BRD2_HUMAN
Homo sapiens
Bromodomain-containing protein 2

PDB Structure

PDB 4UYH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Discovery of I-Bet726 (Gsk1324726A), a Potent Tetrahydroquinoline Apoa1 Up-Regulator and Selective Bet Bromodomain Inhibitor.
Gosmini, R., Nguyen, V.L., Toum, J., Simon, C., Brusq, J.M., Krysa, G., Mirguet, O., Riou-Eymard, A.M., Boursier, E.V., Trottet, L., Bamborough, P., Clark, H., Chung, C.W., Cutler, L., Demont, E.H., Kaur, R., Lewis, A.J., Schilling, M.B., Soden, P.E., Taylor, S., Walker, A.L., Walker, M.D., Prinjha, R.K., Nicodeme, E.
J.Med.Chem.