CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family Putrescine aminotransferase

Enzyme Information

2.6.1.82
Putrescine--2-oxoglutarate transaminase.
based on mapping to UniProt P42588
Putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O.
-!- The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.2.1.19. -!- Cadaverine and spermidine can also act as substrates. -!- Forms part of the arginine catabolism pathway. -!- Cf. EC 2.6.1.113.

UniProtKB Entries (1)

P42588
PAT_ECOLI
Escherichia coli K-12
Putrescine aminotransferase

PDB Structure

PDB 4UOY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Putrescine Aminotransferase from Escherichia Coli Provides Insights Into the Substrate Specificity Among Class III Aminotransferases.
Cha, H.J., Jeong, J., Rojviriya, C., Kim, Y.
Plos One