CATH Classification

Domain Context

CATH Clusters

Superfamily Exo-inulinase; domain 1
Functional Family galactocerebrosidase precursor

Enzyme Information

3.2.1.46
Galactosylceramidase.
based on mapping to UniProt P54818
D-galactosyl-N-acylsphingosine + H(2)O = D-galactose + N-acylsphingosine.
-!- Cf. EC 3.2.1.62.

UniProtKB Entries (1)

P54818
GALC_MOUSE
Mus musculus
Galactocerebrosidase

PDB Structure

PDB 4UFM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Hill, C.H., Viuff, A.H., Spratley, S.J., Salamone, S., Christensen, S.H., Read, R.J., Moriarty, N.W., Jensen, H.H., Deane, J.E.
Chem.Sci.