CATH Domain 4uf0A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.58	Methane Monooxygenase Hydroxylase; Chain G, domain 1
	1.20.58.1370

Domain Context

CATH Clusters

Superfamily	1.20.58.1370
Functional Family	lysine-specific demethylase 6A isoform X2

Enzyme Information

1.14.11.-

With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.

based on mapping to UniProt O14607

UniProtKB Entries (1)

UTY_HUMAN

Homo sapiens

Histone demethylase UTY

PDB Structure

PDB	4UF0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Johansson, C., Velupillai, S., Tumber, A., Szykowska, A., Hookway, E.S., Nowak, R.P., Strain-Damerell, C., Gileadi, C., Philpott, M., Burgess-Brown, N., Wu, N., Kopec, J., Nuzzi, A., Steuber, H., Egner, U., Badock, V., Munro, S., Lathangue, N.B., Westaway, S., Brown, J., Athanasou, N., Prinjha, R., Brennan, P.E., Oppermann, U. Nat.Chem.Biol.