CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome-c3 hydrogenase, C-terminal domain
Functional Family

Enzyme Information

1.12.2.1
Cytochrome-c3 hydrogenase.
based on mapping to UniProt E1K248
H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.
-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

E1K248
E1K248_DESFR
Desulfovibrio fructosivorans JJ
Hydrogenase (NiFe) small subunit HydA

PDB Structure

PDB 4UEQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
[NiFe]-hydrogenases revisited: nickel-carboxamido bond formation in a variant with accrued O2-tolerance and a tentative re-interpretation of Ni-SI states.
Volbeda, A., Martin, L., Liebgott, P.P., De Lacey, A.L., Fontecilla-Camps, J.C.
Metallomics